THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, losing its ability to covalently bind to the C312 cysteine residue of CDK7. Its CDK7 inhibitory activity is weaker than that of THZ1.
Molekulargewicht:
568.07
CAS Nummer:
[1621523-07-6]
Formel:
C31H30ClN7O2
Target-Kategorie:
CDK
T13153
T13153
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