Dasatinib monohydrate, CAS [[863127-77-9]]

Artikelnummer: TGM-T1448L
Artikelname: Dasatinib monohydrate, CAS [[863127-77-9]]
Artikelnummer: TGM-T1448L
Hersteller Artikelnummer: T1448L
Alternativnummer: TGM-T1448L-1MLX10MM(INDMSO),TGM-T1448L-1G,TGM-T1448L-50MG,TGM-T1448L-100MG,TGM-T1448L-500MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: BMS-354825 Monohydrate
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
Molekulargewicht: 506.03
Reinheit: >99.99%
CAS Nummer: [863127-77-9]
Formel: C22H28ClN7O3S
Target-Kategorie: Ephrin Receptor|||Autophagy|||Apoptosis|||c-Kit|||Src|||Bcr-Abl
T1448L