Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor (gamma-secretase) that inhibits Amyloid-beta production with nanomolar potency, selectively inhibits cleavage of APP in cellular level Notch cleavage assays, reverses situational memory deficits, and can be used to study Alzheimers disease.
Molekulargewicht:
391.74
CAS Nummer:
[769169-27-9]
Formel:
C9H8ClF6NO3S2
Target-Kategorie:
Gamma-secretase|||Beta Amyloid
T14525
T14525
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