Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-HT2B, and 5-HT7 receptors with Kis of 0.19 nM and 2.7 nM, respectively. Brilaroxazine can be used for research about cognitive impairments in neuropsychiatric and neurological diseases.
Molekulargewicht:
450.36
Reinheit:
99.36%
CAS Nummer:
[1239729-06-6]
Formel:
C22H25Cl2N3O3
Target-Kategorie:
5-HT Receptor|||Dopamine Receptor
T14782
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