CBR-5884, CAS [[681159-27-3]]

Produktübersicht

• Artikelname: CBR-5884, CAS [[681159-27-3]]
• Artikelnummer: TGM-T14884
• Hersteller Artikelnummer: T14884
• Alternativnummer: TGM-T14884-1MLX10MM(INDMSO),TGM-T14884-1MG,TGM-T14884-5MG,TGM-T14884-10MG,TGM-T14884-25MG,TGM-T14884-50MG,TGM-T14884-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 µM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis. Biochemical characterization of the inhibitor revealed that it was a noncompetitive inhibitor that showed a time-dependent onset of inhibition and disrupted the oligomerization state of PHGDH

Produkteigenschaften

• Molekulargewicht: 336.39
• Reinheit: 99.97%
• CAS Nummer: [681159-27-3]
• Formel: C14H12N2O4S2
• Target-Kategorie: Dehydrogenase

Bilder

T14884