Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.
Molekulargewicht:
635.82
Reinheit:
98.12%
CAS Nummer:
[1384860-29-0]
Formel:
C32H45N9O3S
Target-Kategorie:
FAK|||ALK|||PYK2
T14997
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