Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively).
Molekulargewicht:
266.68
Reinheit:
99.44%
CAS Nummer:
[57653-26-6]
Formel:
C11H11ClN4O2
Target-Kategorie:
Apoptosis|||GluR
T15275
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