FTY720 (S)-Phosphate, CAS [[402616-26-6]]

Produktübersicht

• Artikelname: FTY720 (S)-Phosphate, CAS [[402616-26-6]]
• Artikelnummer: TGM-T15354
• Hersteller Artikelnummer: T15354
• Alternativnummer: TGM-T15354-1MG,TGM-T15354-2MG,TGM-T15354-5MG,TGM-T15354-10MG,TGM-T15354-25MG,TGM-T15354-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: (S)-FTY720 phosphate , (S)-FTY720P

Produktbeschreibung

FTY720 (S)-Phosphate is the active stereoisomeric phosphate derivative of FTY720 that acts as a potent modulator of sphingosine-1-phosphate (S1P) receptors. FTY720 (S)-Phosphate binds to S1P receptor subtypes S1P1, S1P3, S1P4, and S1P5 with Ki values of 2.1, 5.9, 23, and 2.2 nM respectively, causing receptor internalization on lymphocytes, preventing S1P-mediated lymphocyte egress from lymphoid tissues. FTY720 (S)-Phosphate also enhances endothelial barrier integrity, stimulates transporters such as Abcb1 and Abcc1, and inhibits cytosolic phospholipase A2 activity, highlighting its multifunctional pharmacological properties, making it an compound of interest in the research of diseases including multiple sclerosis, autoimmune diseases and cancer.

Produkteigenschaften

• Molekulargewicht: 387.45
• Reinheit: 99.37%
• CAS Nummer: [402616-26-6]
• Formel: C19H34NO5P
• Target-Kategorie: S1P Receptor|||LPL Receptor

Bilder

T15354

T15354