GSK180 is a selective, competitive, and highly potent inhibitor of kynurenine-3-monooxygenase (KMO), a critical enzyme in the tryptophan metabolic pathway, with an IC50 value of approximately 6 nM, displaying minimal off-target activity against other tryptophan pathway enzymes, rapidly altering kynurenine metabolite profiles, GSK180 serves as a powerful research tool for probing the biological and therapeutic implications of KMO inhibition in metabolic, neurological, and inflammatory disease models.
Molekulargewicht:
276.07
CAS Nummer:
[1799725-26-0]
Formel:
C10H7Cl2NO4
Target-Kategorie:
Hydroxylase
T15426
T15426
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