Rebamipide, CAS [[90098-04-7]]
Artikelnummer:
TGM-T1562
- Bilder (1)
| Artikelname: | Rebamipide, CAS [[90098-04-7]] |
| Artikelnummer: | TGM-T1562 |
| Hersteller Artikelnummer: | T1562 |
| Alternativnummer: | TGM-T1562-1G |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | Proamipide , OPC12759 |
| Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense. |
| Molekulargewicht: | 370.79 |
| Reinheit: | 0.999 |
| CAS Nummer: | [90098-04-7] |
| Formel: | C19H15ClN2O4 |
| Target-Kategorie: | Prostaglandin Receptor|||Free radical scavengers|||COX |

