Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively).
Molekulargewicht:
587.17
Reinheit:
95.56%
CAS Nummer:
[136668-42-3]
Formel:
C34H35ClN2O3S
Target-Kategorie:
FLAP|||Apoptosis
T16087
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