ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 µM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
Molekulargewicht:
361.29
Reinheit:
99.60%
CAS Nummer:
[105637-50-1]
Formel:
C15H18Cl2N2O2S
Target-Kategorie:
Akt|||Myosin|||Calcium Channel
T16104
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