Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin that inhibits cyclooxygenase. It induces cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells by down-regulating EGFR/PI3K/STAT3 signaling and modulating Bcl-2 family proteins. Additionally, Nitroaspirin possesses antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
Molekulargewicht:
331.28
Reinheit:
98.45%
CAS Nummer:
[175033-36-0]
Formel:
C16H13NO7
Target-Kategorie:
COX|||Apoptosis
T16328
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