NSC745885 is an antitumor agent non-toxic to normal cells that downregulates EZH2 via proteasome-mediated degradation. It exhibits toxicity against multiple normal and drug-resistant cancer cell lines and may be used in studies of advanced bladder cancer and oral squamous cell carcinoma.
Molekulargewicht:
266.27
CAS Nummer:
[4219-52-7]
Formel:
C14H6N2O2S
Target-Kategorie:
Apoptosis|||Histone Methyltransferase
T16354
T16354
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