Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Olutasidenib is a highly effective, brain penetrant, and selective inhibitor of the mutant Isocitrate dehydrogenase 1 (IDH1) (IC50: 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively).
Molekulargewicht:
354.79
Reinheit:
98.57%
CAS Nummer:
[1887014-12-1]
Formel:
C18H15ClN4O2
Target-Kategorie:
Isocitrate Dehydrogenase (IDH)|||Dehydrogenase
T16384
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