sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels. Myc is a multifunctional nuclear phosphoprotein that plays a key role in cell cycle progression, apoptosis, and cellular transformation. sAJM589 inhibits the cellular proliferation of a variety of Myc-dependent cancer cell lines and the adherent, non-dependent growth of Raji cells Growth.
Molekulargewicht:
246.26
CAS Nummer:
[2089-82-9]
Formel:
C16H10N2O
Target-Kategorie:
c-Myc
T16839
T16839
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