SD-36 TFA is a selective and highly efficient STAT3 degrader with a Kd value of about 50 nM.SD-36 has anticancer and antitumor activity, and can break down mutant STAT3 proteins in cells and inhibit STAT3 transcription.SD-36 promotes growth inhibition and induces apoptosis through inhibition of Mcl-1 in gliomas.
Molekulargewicht:
1272.17
Reinheit:
98.43%
Formel:
C61H63F5N9O14P
Target-Kategorie:
Apoptosis|||STAT
T18680L
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