LOM612 is a potent and specific FOXO relocator that induces nuclear translocation of the FOXO3a reporter protein as well as endogenous FOXO3a and FOXO1 in a dose-dependent manner in U2OS cells, down-regulates the expression of c-Myc and cyclin D1, and has anti-proliferative effects in human cancer cell lines.
Molekulargewicht:
258.3
CAS Nummer:
[2173232-79-4]
Formel:
C13H10N2O2S
Target-Kategorie:
FOXO
T19405
T19405
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