AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
Molekulargewicht:
420.5
Reinheit:
97.55%
CAS Nummer:
[2088113-98-6]
Formel:
C24H28N4O3
Target-Kategorie:
ATM/ATR
T19671
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