Colcemid (NSC-3096) is a microtubule polymerization inhibitor that primarily targets tubulin, with an IC50 of 2.4 µM. Demecolcine interacts with tubulin dimers, induces antimitotic effects, and inhibits microtubule growth. Colcemid is a classic reagent used in karyotyping, banding techniques, and cell cycle synchronization. Colcemid can induce apoptosis and is used in studies of tumor and embryonic cloning.
Molekulargewicht:
371.43
Reinheit:
99.65%
CAS Nummer:
[477-30-5]
Formel:
C21H25NO5
Target-Kategorie:
Apoptosis|||Microtubule Associated
T19720
T19720
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