MRT-92, CAS [[1428315-82-5]]

Artikelnummer: TGM-T200033
Artikelname: MRT-92, CAS [[1428315-82-5]]
Artikelnummer: TGM-T200033
Hersteller Artikelnummer: T200033
Alternativnummer: TGM-T200033-25MG,TGM-T200033-50MG,TGM-T200033-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.
Molekulargewicht: 566.65
CAS Nummer: [1428315-82-5]
Formel: C33H34N4O5
Target-Kategorie: Hedgehog/Smoothened|||Smo
T200033