AJI-100, CAS [[844435-10-5]]

Produktübersicht

• Artikelname: AJI-100, CAS [[844435-10-5]]
• Artikelnummer: TGM-T200052
• Hersteller Artikelnummer: T200052
• Alternativnummer: TGM-T200052-25MG,TGM-T200052-50MG,TGM-T200052-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective IC50 values of 12.7 nM and 18.5 nM. It inhibits T cell mitosis and cell polarity by directly targeting Aurora kinase A and reduces STAT3 phosphorylation by inhibiting JAK2 activation, consequently diminishing the differentiation of TH1 and TH17 cells. This compound is utilized in researching immune response regulation and the prevention of graft-versus-host disease (GVHD).

Produkteigenschaften

• Molekulargewicht: 323.32
• CAS Nummer: [844435-10-5]
• Formel: C17H14FN5O
• Target-Kategorie: JAK|||Aurora Kinase|||STAT

Bilder

T200052