Topoisomerases/ribosomes-IN-1 (compound 30f) serves as an inhibitor targeting both ribosomes and topoisomerases, specifically exhibiting inhibitory actions against constitutively macrolide-resistant bacteria. This compound effectively suppresses bacterial protein synthesis (IC 50 : 0.647 µM) and hampers DNA replication (IC 50 : 0.218 µM).
Molekulargewicht:
1063.26
Formel:
C53H83FN6O15
Target-Kategorie:
Topoisomerase
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