Apoptosisinducer 25 (Compound 4H) demonstrates potent anticancer capabilities by inhibiting the proliferation of BGC-823 cancer cells with an IC50 of 0.37 µM. It induces apoptosis in BGC-823 cells, causes mitochondrial dysfunction, and arrests the cell cycle at the G2/M phase. Additionally, Apoptosisinducer 25 exhibits favorable pharmacokinetic properties in rats.
Molekulargewicht:
683.87
CAS Nummer:
[2763063-15-4]
Formel:
C42H53NO7
Target-Kategorie:
Apoptosis
T200268
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