MK-3168 (12C) functions as a FAAH inhibitor, exhibiting IC50 values of 1.0 nM, 5.5 nM, and 1.7 nM for human, rhesus, and rat respectively. It demonstrates effective brain uptake and FAAH-specific signaling. Additionally, 11 C MK-3168 is applicable as a FAAH PET tracer.
Molekulargewicht:
412.94
CAS Nummer:
[1242441-26-4]
Formel:
C21H21ClN4OS
Target-Kategorie:
FAAH
T200270
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