ERalpha degrader10 is a potent, selective, orally active estrogen receptor alpha (ERalpha) degrader. It demonstrates strong ERalpha binding affinity (IC50 of 24.0 nM) and degradation capability (EC50 of 5.3 nM). This compound degrades ERalpha through a proteasome-mediated pathway and is utilized in breast cancer research.
Target-Kategorie:
Estrogen Receptor/ERR
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