PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-gamma. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.
Target-Kategorie:
PD-1/PD-L1
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