(1-Nitroethene-1,2-diyl)dibenzene (alpha-Nitrostilbene, alpha-Nitrostilbene) serves as an inhibitor of protein arginine methyltransferase 1 (PRMT1, histone H4 methylation assay with an IC50 of 11 µM). At concentrations of 10 and 100 µM, it also inhibits histone H4 methylation caused by PRMT8 but does not affect methylation of histone H3.1 induced by CARM1 or Set7/9.
Molekulargewicht:
225.24
CAS Nummer:
[1215-07-2]
Formel:
C14H11NO2
Target-Kategorie:
Histone Methyltransferase|||Others
T200869
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