Menin-MLL inhibitor 34 (Compound 37) is a selective and potent inhibitor of Menin-MLL, exhibiting an IC50 of 18.21 nM against Menin. This compound effectively reduces Menin protein levels and downregulates MEN1 transcription, demonstrating sustained anti-leukemia effects.
Molekulargewicht:
775.98
Formel:
C40H54FN9O4S
Target-Kategorie:
Epigenetic Reader Domain
T200907
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