Rosiglitazone sodium is an effective and selective PPARgamma activator, with EC50 values of 30 nM for PPARgamma1, 100 nM for PPARgamma2, and 60 nM for PPARgamma. It also has an approximate Kd of 40 nM for PPARgamma. Additionally, Rosiglitazone sodium acts as a regulator of TRP channels, inhibiting the activities of TRPM2 and TRPM3, while activating TRPC5.
Molekulargewicht:
379.41
CAS Nummer:
[316371-83-2]
Formel:
C18H18N3NaO3S
Target-Kategorie:
Autophagy|||PPAR|||TRP/TRPV Channel
T200945
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