PROTAC EZH2 Degrader-3 (compound ZJ-20) is a potent EZH2 degrader that exhibits strong inhibitory effects not only on EZH2 protein expression but also on the levels of other PRC2 subunits and H3k27me3 protein. Additionally, PROTAC EZH2 Degrader-3 demonstrates antiproliferative activity by blocking the cell cycle at the G0-G1 phase and inducing apoptosis (cell death). At a concentration of 5 µM and over a period of 24 hours, it effectively suppresses the expression of these critical proteins involved in cell regulation and growth.
Molekulargewicht:
981.19
Formel:
C56H68N8O8
Target-Kategorie:
Histone Methyltransferase|||PROTACs|||Apoptosis
T200955
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
