Abeta-IN-10 (Compound Alz-5) is a bifunctional copper chelator and an inhibitor of beta-amyloid (Abeta), interacting with Abeta aggregates to reduce their neurotoxicity. This compound also displays antioxidative properties and exhibits moderate cytotoxicity in SH-SY5Y and HepG2 cells in the presence of CuCl2, with IC50 values of 65.5 and 31.2 µM, respectively. Additionally, Abeta-IN-10 reduces the increase in cell rigidity caused by Abeta.
Molekulargewicht:
557.78
Formel:
C30H35N7S2
Target-Kategorie:
Beta Amyloid
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
