NLRP3-IN-55 (Compound 19) is an effective inhibitor of NLRP3, exhibiting an inhibitory concentration (IC50) of 0.34 µM. It targets the NLRP3 protein directly with a dissociation constant (KD) of 0.45 µM, effectively blocking the assembly and activation of the NLRP3 inflammasome. This action results in anti-inflammatory effects and inhibits cell pyroptosis.
Molekulargewicht:
561.04
Formel:
C32H30ClFN2O4
Target-Kategorie:
Pyroptosis|||NOD-like Receptor (NLR)
T201017
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