AubipyOMe serves as an effective inhibitor of Tartrate-resistant Acid Phosphatase (TRAP/ACP5), a metalloenzyme identified in activated osteoclasts and macrophages. It exhibits inhibitory IC50 values of 1.3 µM against TRAP5a and 1.8 µM against TRAP5b. Additionally, it effectively suppresses TRAP activity in extracts from mouse macrophages and human lung tissues.
Molekulargewicht:
629.07
CAS Nummer:
[1221591-26-9]
Formel:
C12H12AuCl2F6N2O2P
Target-Kategorie:
Others|||Endogenous Metabolite
T201150
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