PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 µM (Bovine LOX), 3.2 µM (rh LOXL1), 0.6 µM (rh LOXL2), 1.4 µM (rh LOXL3), and 0.2 µM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.
Molekulargewicht:
265.73
CAS Nummer:
[2409964-40-3]
Formel:
C10H13ClFNO2S
Target-Kategorie:
Monoamine Oxidase
T201314
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