AZ 14145845, CAS [[2830555-70-7]]

Produktübersicht

• Artikelname: AZ 14145845, CAS [[2830555-70-7]]
• Artikelnummer: TGM-T201375
• Hersteller Artikelnummer: T201375
• Alternativnummer: TGM-T201375-25MG, TGM-T201375-50MG, TGM-T201375-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

AZ 14145845, a potent and highly selective dual Mer/Axl kinase inhibitor (pIC50 = 7 nM and 7.8 nM in pAxl and pMer, respectively), demonstrates significant efficacy in reducing tumor growth in a dose-dependent manner within the Mer and Axl kinase Ba/F3 tumor xenograft model in vivo. When combined with anti-PD1 antibodies and ionizing radiation, this compound enhances survival rates in mice bearing MC38-derived tumors. Additionally, AZ 14145845 is orally bioavailable.

Produkteigenschaften

• Molekulargewicht: 561.68
• CAS Nummer: [2830555-70-7]
• Formel: C32H35N9O

Bilder

T201375