NPD6433 is a triazole indole compound that exhibits broad-spectrum activity against all screened fungal strains. It targets the enoyl reductase domain of fatty acid synthase 1 (Fas1), covalently inhibiting its flavin mononucleotide-dependent NADPH oxidase activity, thereby blocking the biosynthesis of essential fatty acids.
Molekulargewicht:
391.42
Formel:
C21H21N5O3
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