NOD1-RIPK2-IN-1 (Compound 37) is an inhibitor of the NOD1-RIPK2 signaling pathway, displaying potent IC50 values of 42 nM and 1.52 nM against NOD1 and RIPK2, respectively. This compound effectively reduces the secretion of the pro-inflammatory cytokine IL-8, making it valuable for research in inflammation and immune disorders.
Molekulargewicht:
465.37
Formel:
C22H26Cl2N4O3
Target-Kategorie:
RIP kinase|||NOD-like Receptor (NLR)
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