(S)-ACE-OH is a molecular glue with anticancer activity, functioning by inducing interaction between the E3 ubiquitin ligase TRIM21 and the nuclear pore protein NUP98. This interaction facilitates the degradation of nuclear pore proteins and disrupts nucleocytoplasmic transport.
Molekulargewicht:
328.47
Formel:
C19H24N2OS
Target-Kategorie:
Molecular Glues
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