Methacycline, a tetracycline antibiotic, inhibits bacterial protein synthesis and effectively suppresses epithelial-mesenchymal transition (EMT). It blocks EMT in vitro and inhibits fibrogenesis in vivo without directly affecting the TGF-beta1Smad signaling pathway. As an antimicrobial agent, Methacycline holds potential for research in pulmonary fibrosis.
Molekulargewicht:
442.42
CAS Nummer:
[914-00-1]
Formel:
C22H22N2O8
Target-Kategorie:
CaSR|||Antibiotic
T201726
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