ERK1/2 inhibitor 11 (compound L6) is a dual inhibitor of ERK1/2 that promotes the accumulation of DSBs and the degradation of ERK1/2 expression. This compound decreases BCL-2 levels and induces DNA damage by inhibiting PARP and ERK1/2. Additionally, ERK1/2 inhibitor 11 activates caspase 3 to induce apoptosis.
Molekulargewicht:
333.41
Formel:
C15H19N5O2S
Target-Kategorie:
Apoptosis|||ERK|||Caspase
T201740
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