PF-477736 2HCl, CAS [[1247874-19-6]] Preis auf Anfrage
Artikelnummer:
TGM-T202968
Hersteller Artikelnummer:
T202968
Alternativnummer:
TGM-T202968-10MG,TGM-T202968-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
PF-477736, also known as PF-00477736, is a potent CHK1 inhibitor with potential to enhance chemotherapy. This compound inhibits CHK1, an ATP-dependent serine/threonine kinase that is a crucial component of the S/G2 checkpoint system for DNA replication monitoring. By bypassing the final checkpoint defenses against DNA damage-induced lethal effects, PF-477736 may improve the antitumor efficacy of various chemotherapeutic agents in tumor cells with inherent checkpoint deficiencies.
Molekulargewicht:
492.4
CAS Nummer:
[1247874-19-6]
Formel:
C22H27Cl2N7O2
T202968
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