PRDX1-IN-3 (SOMCL-19-048) is a PRDX1 covalent inhibitor with anti-colorectal cancer activity. PRDX1-IN-3 can effectively inhibit the proliferation of colorectal cancer cells and significantly reduce the anti-tumor effect on colorectal cancer nude mice carrying PRDX1 gene knockout. PRDX1-IN-3 can also upregulate downstream genes of the p53 signaling pathway and exert anti-cancer effects.
Molekulargewicht:
550.73
CAS Nummer:
[2566976-46-1]
Formel:
C33H46N2O5
Target-Kategorie:
MDM-2/p53|||Reactive Oxygen Species
T203007
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