D5B is an effective and selective PD-L1 inhibitor that has been modified with DBCO. It degrades PD-L1 in 4T1 and B16-F10 tumor cells with EC50 values of 5.4 µM and 6.2 µM, respectively. D5B can block the PD-L1/PD-1 interaction and exhibits antitumor activity.
Molekulargewicht:
983.15
Formel:
C58H66N2O12
Target-Kategorie:
PD-1/PD-L1
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