4-Epidoxycycline is a hepatic metabolite of the antibiotic doxycycline and lacks antibiotic properties in mice. In both in vitro assays and in vivo mouse models, 4-Epidoxycycline regulates HER2 gene expression similarly to doxycycline and exhibits comparable efficacy in tumor tissues, achieving over 95% tumor regression rates.
Molekulargewicht:
444.44
CAS Nummer:
[6543-77-7]
Formel:
C22H24N2O8
Target-Kategorie:
EGFR
T203210
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