ZG-2033 (Compound 26) is an orally active HIF-2alpha agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.
Molekulargewicht:
286.35
CAS Nummer:
[2685739-28-8]
Formel:
C15H14N2O2S
Target-Kategorie:
HIF/HIF Prolyl-Hydroxylase
T203229
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