UKH-1114 is a potent sigma2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.
Molekulargewicht:
375.43
CAS Nummer:
[2113664-14-3]
Formel:
C22H24F3NO
Target-Kategorie:
Sigma receptor
T203242
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