LH1513 is a dioxalate salt derivative of l-lysine that inhibits CaOx crystallization more effectively than citrate and pyruvate. It shows potential preventive activity in hyperoxaluria models and effectively prevents urinary CaOx crystal formation in Agxt knockout mice. AGXT-1 is a mitochondrial protein involved in metabolic processes.
Molekulargewicht:
356.17
Formel:
C10H11N2Na3O8
Target-Kategorie:
Mitochondrial Metabolism
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