GAPDH-IN-1 (Compound F8) is a GAPDH inhibitor, with an IC50 value of 39.31 µM for GAPDH enzyme activity. It forms a covalent adduct with the aspartic acid in the active site, displacing the enzymes cofactor NAD+, and simultaneously enhances the reactivity of cysteine-reactive probes with the catalytic cysteine.
Molekulargewicht:
366.37
CAS Nummer:
[252212-58-1]
Formel:
C20H18N2O5
Target-Kategorie:
Endogenous Metabolite
T203346
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