Apoptosisinducer 32 (Compound 7g) is an apoptosis inducer with a KD of 42 µM, demonstrating antitumor activity by causing significant morphological changes, such as membrane blebbing, nuclear fragmentation, and apoptotic body formation, in MDA-MB-231 cells. The IC50 values for Apoptosisinducer 32 are 4.77 µM in MCF-7 cells, 6.56 µM in MDA-MB-231 cells, and 337.8 µM in HEK cells.
Molekulargewicht:
616.45
Formel:
C29H27Cl2N3O8
Target-Kategorie:
Apoptosis
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